Their purpose is to reduce inflammation, suppress immune system response, constrict blood vessels in the skin.
Using corticosteroids is the equivalent of using Aloe Vera for sunburns while remaining in the sun and not seeking shade.
Sure, the hormones Auxin and Gibberellins in Aloe Vera have wound healing and anti-inflammatory properties that can help sunburns a lot, but they become less effective if the main cause of the sunburn (the sun) continues to shine relentlessly on your skin.
The long-term use of corticosteroids can also cause thinning of the skin and their effectiveness reduces or may stop working completely over time.
Though it is not cortisone, it is a strong medicine that can cause your skin to become irritated and sore, if without the potential for withdrawal. It takes several weeks to start working, but once it does, It generally stops psoriasis for a longer period of time when compared to corticosteroids.
This medication works by slowing skin cells growth. It accumulates over time in the mitochondria, interfering with the supply of energy to the cells thus impeding DNA cell replication.
Besides irritating the skin, this medication also stains the skin with a brownish color and will permanently stain clothes.
Calcineurin inhibitors (tacrolimus, pimecrolimus)
Like Corticosteroids, these immunosuppressive medications aim to reduce inflammation and plaque buildup. They are specially used in thin sensitive areas of the skin where steroid creams may be too irritating to use.